About Us.

The company behind the science.

About Aerpio

Aerpio Therapeutics is a biopharmaceutical company focused on the development of novel therapeutics for vascular disorders with a concentration on diseases of the eye.

Our lead programs include a Tie-2 activator for diabetic macular edema (DME) and a hypoxia-inducible factor 1-α (HIF1-α) stabilizer for the treatment of inflammatory bowel disease. The lead compound for the Tie-2 program, AKB-9778, recently completed a proof-of-concept, phase 2A study (TIME-2), and the HIF1-α stabilization program is rapidly progressing toward the clinic with first-in-human trials expected to start in early 2016.

Advisory Board

Name Organization
Randall Johnson, PhD Oxford University
Peter Campochiaro, MD Johns Hopkins School of Medicine
Dietmar Vestweber, PhD Max Planck Institute
Chris Kontos, MD Duke University School of Medicine
Sean Colgan, PhD University of Colorado Denver
Susan Quaggin, MD Northwestern University Feinberg School of Medicine
Robert Shalwitz, MD

Clincal Advisory Board - Ophthalmology

Name Organization
Peter Campochiaro, MD Wilmer Eye Institute, Johns Hopkins School of Medicine
Jeffrey Heier, MD Ophthalmic Consultants of Boston
Pravin Dugel, MD Retina Consultants of Arizon
Peter Kaiser, MD Cole Eye Institute, Cleveland Clinic
David Boyer, MD Retina-Vitreous Associates Medical Group

Board Members

Director Campbell Murray, M.D., Novartis Venture Fund
Director Reinhard Ambros, Ph.D., Novartis Venture Fund
Director Muneer Satter, Satter Investment Management LLC
Director Chau Q. Khuong, Private Equity Partner, OrbiMed Healthcare Fund Management
Director Anupam Dalal, M.D., Kearny Venture Partners
Director Paul Weiss, Ph.D., Venture Investors, LLC
Director John Rice, Ph.D., Triathlon Medical Ventures
Director Joseph Gardner, Ph.D., Aerpio Therapeutics, Inc.
Director Duane Nash, M.D., J.D., M.B.A., Vital Therapies, Inc.
Director Adrienne L. Graves, Ph.D., Board Member at the American Society for Cataract & Refractive Surgery Foundation, Glaucoma Research Foundation, Advisory Board Member at The Foundation of the American Academy of Ophthalmology