Tie 2 Symposium

A World of Indications

For one small molecule, AKB-9778 has a huge potential.

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World of Indications

New Approach for IBD

AKB-4924 strengthens the immune system and epithelial cells of the gut in preclinical models.

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IBD Pill

Aerpio Therapeutics is a biopharmaceutical company focused on the development of novel therapeutics for vascular disorders with a concentration on diseases of the eye.

Our lead programs include a Tie-2 activator for diabetic macular edema (DME) and a hypoxia-inducible factor 1-α (HIF1-α) stabilizer for the treatment of inflammatory bowel disease. The lead compound for the Tie-2 program, AKB-9778, recently completed a proof-of-concept, phase 2A study (TIME-2), and the HIF1-α stabilization program is rapidly progressing toward the clinic with first-in-human trials expected to start in early 2016.

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Aerpio Pipeline

11/17/15 - Aerpio Therapeutics Reports Positive Clinical Results from the Phase 2a Study of Lead Candidate, AKB-9778, in Diabetic Macular Edema (DME): The TIME-2 Trial

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10/9/15 - Aerpio Therapeutics to Present TIME-2 Phase 2a Study of AKB-9778 in Diabetic Macular Edema Data at 2015 American Academy of Ophthalmology Annual Meeting Retina Subspecialty Day

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10/7/15 - Aerpio Appoints Steve Pakola, M.D. as Chief Medical Officer

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