A Paradigm Shift

in the treatment of diabetic eye disease

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World of Indications

New Approach for IBD

Orally-administered, once-daily AKB-4924 is the only drug candidate in development that directly addresses both inflammation and mucosal wound healing.

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IBD Pill
Tie 2 Symposium

Aerpio Therapeutics is a biopharmaceutical company focused on the development of novel therapeutics for vascular disorders with a concentration on diseases of the eye.

Our lead programs include a Tie2 activator for diabetic retinopathy (DR) and a hypoxia-inducible factor 1-α (HIF-1-α) stabilizer for the treatment of inflammatory bowel disease. The lead compound for the Tie2 program, AKB-9778, recently completed a proof-of-concept, phase 2a study (TIME-2). AKB-4924, the lead compound in our and the HIF-1-α stabilization program, has recently completed a Phase 1a study.

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Aerpio Pipeline

3/16/17 - Aerpio Pharmaceuticals Raises $40 Million

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3/8/17 - Aerpio Therapeutics to Present at the Cowen and Company 37th Annual Health Care Conference

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6/13/16 - Aerpio Therapeutics Reports Peer-Reviewed Publication of Positive Clinical Results from the Phase 2a Study of Lead Candidate, AKB-9778, in Diabetic Macular Edema (DME): The TIME-2 Trial

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